Calligraphy and ACTG pattern
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Overview
Vast amounts of genomic data are created as part of the genome sequencing efforts ongoing globally. This high-throughput data production enables a shift from hypothesis driven to discovery based science. With this shift comes the need to create ways of extracting information and creating knowledge from ever-increasing amounts of data in world-wide databases. In parallel to this trend is an increasing need to address ever more complex questions and problems that face us globally in the 21st Century.

Ecce Homology is an artwork that offers a unique and alternative approach to visualizing and interacting with large amounts of genomic data.  It also demonstrates the potential for novelty that collaboration between the arts and sciences can create and the possibility for the arts to nurture discovery in the sciences.

visitors to the installation
 

Ecce Homology presents genomic data through a novel visualization composed of calligraphic forms, or pictographs, representing the protein products encoded by genes. The pictographs are created by using genomic and protein data to drive a virtual calligraphic brush.

Genes from human beings and the rice plant that comprise the metabolic pathways for cellular respiration (the process by which carbohydrate is broken down into carbon dioxide in order to release the energy necessary for life) have been used to create the pictographs for the installation.The pictographs are therefore a metaphor for the cycling of energy and carbon and the underlying unity of life as reflected in biological processes.

Within the installation, human genes are presented on the vertical axis and genes from the rice plant are presented on the horizontal  axis of a 40-foot wide by 12-foot tall projection. A full-body computer vision interface enables multiple visitors to interact with the installation and select human genes to undergo BLAST analysis.

Human picctographs on the vertical, rice pictographs on the horizontal
 
 
 
         
         
         
         
brush strokes enlarged
brush strokes enlarged
brush strokes enlarged